leeches leech mehdi leech (Hirudotherapy) therapist Cardiovascular Disease and Leech Therapy IN NEW ZEALAND
Cardiovascular Disease and Leech Therapy
Since the early days of the 20th century, people have been using leeches to treat cardiovascular diseases because of the Hirudin enzyme in the leeches saliva, a substance which has systemic anticoagulative effects. A physician would usually prescribe the use of leeches when a person suffered a stroke or heart attack. Also, Hirudin stimulates segmental reflex mechanisms and this contributes to the treatment of cardiovascular diseases.
Hirudin and Drugs
It was only when anticoagulants such as aspirin and heparin were invented that the use of leeches declined. The effects of aspirin which are the inhibition of platelet aggregation and for the dissolving of thrombus or embolus, or thrombolysis, were found to be much more effective in treating cardiovascular conditions. However, scientists began to investigate further uses of Hirudin for cardiovascular conditions and they found Recombinant Hirudin was useful for Myocardial Infarctions (MI) and unlike heparin; hirudin was actually a direct thrombin inhibitor which did not need to have a cofactor like antithrombin III. Also, hirudin could inactivate fibrin-bound thrombins. However, the effects of the drugs derived from hirudin were much too potent and caused quite massive hemorrhagic adverse effects. Because of this, hirudin was not considered a good primary treatment for myocardial infarction; however, they found that it was a good treatment for Heparin-induced thrombocytopenia Type 2.
Cardiovascular Disease and Leech Therapy
Since the early days of the 20th century, people have been using leeches to treat cardiovascular diseases because of the Hirudin enzyme in the leeches saliva, a substance which has systemic anticoagulative effects. A physician would usually prescribe the use of leeches when a person suffered a stroke or heart attack. Also, Hirudin stimulates segmental reflex mechanisms and this contributes to the treatment of cardiovascular diseases.
Hirudin and Drugs
It was only when anticoagulants such as aspirin and heparin were invented that the use of leeches declined. The effects of aspirin which are the inhibition of platelet aggregation and for the dissolving of thrombus or embolus, or thrombolysis, were found to be much more effective in treating cardiovascular conditions. However, scientists began to investigate further uses of Hirudin for cardiovascular conditions and they found Recombinant Hirudin was useful for Myocardial Infarctions (MI) and unlike heparin; hirudin was actually a direct thrombin inhibitor which did not need to have a cofactor like antithrombin III. Also, hirudin could inactivate fibrin-bound thrombins. However, the effects of the drugs derived from hirudin were much too potent and caused quite massive hemorrhagic adverse effects. Because of this, hirudin was not considered a good primary treatment for myocardial infarction; however, they found that it was a good treatment for Heparin-induced thrombocytopenia Type 2.
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